Primary Myelofibrosis in a Young Girl- A Case Report

نویسندگان

چکیده

Myelofibrosis (MF) is a rare disorder that classified as one of the myeloproliferative disorders. It BCR-ABL1- negative neoplasm characterized by abnormal proliferation hemopoietic stem cells within bone marrow, which leads to overproduction fibrous tissue. Our patient young girl 17 year old presented with lump in left upper abdomen, shortness breath & generalized swelling. The diagnosis was made based on severe anaemia, pancytopenia peripheral blood film. Bone marrow trephine biopsy from tibia revealed myelofibrosis. Splenectomy done an attempt reduce total volume malignant and improve features hypersplenism. hypersplenism 17- year- reported rarely. However, when it does, usually runs rapid fatal course. J Bangladesh Coll Phys Surg 2023; 41: 239-243

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ژورنال

عنوان ژورنال: Journal of Bangladesh College of Physicians and Surgeons

سال: 2023

ISSN: ['1015-0870', '2309-6365']

DOI: https://doi.org/10.3329/jbcps.v41i3.66913